Buses picked up 123 veterans at the Embassy Suites in Loveland and the motorcade escorted them to Denver International Airport.
This is the 18th trip organized by Honor Flight Northern Colorado.
Supporters gathered on overpasses and along the side of the road along the route to wave flags and cheer the veterans and their motorcade.
The veterans will fly to Baltimore and stay at the Baltimore Hilton Hotel.
On Monday, they’ll take buses to Washington to visit the World War II Memorial, the Air Force Memorial, the Iwo Jima Memorial, the Korean War Veterans Memorial, the Lincoln Memorial and the Vietnam Veterans Memorial.
All of the veterans’ expenses are paid through donations to the Honor Flight Northern Colorado.
Every flight is made up of 120 veterans and 60 or more guardians, according to the group’s website.